Basic Information

Symbol
PRB4
RNA Class
mRNA
Alias
proline rich protein BstNI subfamily 4 Po basic salivary proline-rich protein 4 BstNI type basic salivary proline-rich protein 4 parotid o protein salivary proline-rich protein II-1 salivary proline-rich protein Po Basic salivary proline-rich protein 4 Salivary proline-rich protein Po Parotid o protein Salivary proline-rich protein II-1
Location (GRCh38)
12:11307077-11310436 UCSC Genome Browser
Transcripts
NM_001261399.3
BLAST PRIMER
NM_002723.6
BLAST PRIMER
External Database
-

Secondary Structure

MANE Select
NM_002723.6
Sequence length
923 nt
GC Content
0.5623

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-249.5 kcal/mol
Thermodynamic ensemble
Free Energy: -267.06 kcal/mol
Frequency: 0.0000
Diversity: 205.08
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.(((..(((.((((..((((..(((((.(..((((.....))))..).)))))..))))((((((((.((((((((((.....(((((.(.(((....)))..).))))).(((((((.....)))))))....)))))...))))).))).......((...((((((......((......))......))))))...))...)))))..(((((....((...((((((..(((........)))......))))))...))..........((((...((((....)).))......))))...))))))))).))).....((....)).............((...((((((..(((........)))......))))))...))..(((......((((..........((((((.....(((((..........(((((((...((...................))...))))))).....((((...(((...((..........))...)))....))))....((...((((.(((.....(((((...(.((.........(((((((.........(((((............((((.....))))...)))))......)))))))..(((....)))......(((((((((((............(((...))).)))))))))))...)))...)))))....)))...))))...))(((((((.(.....).))))))).)))))....))))))((((....)).)).(((((((.((((...((..........((.(((((((((.....))))).)))).))))....)).)).)))))))....))))......)))................................)))......
Thermodynamic Ensemble Prediction
.(({..(((,((((..((((..(((((.(..((((,...,))))..).)))))..))))((((((((.((((((((((.....(((((.{.(((....)))..}.))))).(((((((.....)))))))....)))))...))))).})).......{{...((((((......((......))......))))))...))...)))))..(((((....{,...,(({((..,{{........))}......}}}||}.,.||....||....|{{{..,{{{{....)).))......}))}...)))))}}}}.))}.....((....}}.....{,,,....,,...,(((((,.,{{........))}......}})))),,.||....|,.....{{{{..........((((((.....(((((..........,{{((({...||..................,||...|||||||.....{,,,,.,(((.....,}}}..{((((({..,...,..(({{{..,{{....||..(({.....{|||,...{,{,......{||{,,,|||...,}....||||...........{.((((.....))))}..)))))......)))))))..(((....)))......(((((((((((....,,...|..{{|...))}.)))))))))))...||,,..}))))....,..,||}}}}...))|((((((,,.....).))))))}.)))))....))))))((((....}}.)).(((({((.{{,{..,{|..,.......,.,||,((((({.....}))))},}}|,,.....,,}).}).})))))}....)))).,...,|||.....,,,..........,.........,))})))......

Transcripts

ID Sequence Length GC Content
NM_001261399.3 AGCACAGAGUUGGGAGUGACUCCAGAGCCUCCAGCGAGAUGCUGCUGAU… 716 nt 0.5489
NM_002723.6 AGCACAGAGUUGGGAGUGACUCCAGAGCCUCCAGCGAGAUGCUGCUGAU… 923 nt 0.5623
Summary

This gene encodes a member of the heterogeneous family of basic, proline-rich, human salivary glycoproteins. The encoded preproprotein undergoes proteolytic processing to generate one or more mature peptides before secretion from the parotid glands. Multiple alleles of this gene exhibiting variations in the length of the tandem repeats have been identified. The reference genome encodes the "Small"" allele. This gene is located in a cluster of closely related salivary proline-rich proteins on chromosome 12. Alternative splicing results in multiple transcript variants encoding different isoforms that may undergo similar proteolytic processing. [provided by RefSeq

Forensic Context

Nov 2015]"

Genomic Tracks
Track Image