Basic Information

Symbol
PRM2
RNA Class
mRNA
Alias
protamine 2 CT94.2 cancer/testis antigen family 94, member 2 protamine-2 sperm histone P2 sperm protamine P2 testicular secretory protein Li 40 Protamine-2 Sperm histone P2 Sperm protamine P2
Location (GRCh38)
16:11275639-11276480 UCSC Genome Browser
Transcripts
NM_001286356.2
BLAST PRIMER
NM_001286357.2
BLAST PRIMER
NM_001286358.2
BLAST PRIMER
NM_001286359.2
BLAST PRIMER
NM_002762.4
BLAST PRIMER
External Database
HGNC NCBI Ensembl UniProt OMIM GTEx

Secondary Structure

MANE Select
NM_002762.4
Sequence length
680 nt
GC Content
0.5838

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-219.1 kcal/mol
Thermodynamic ensemble
Free Energy: -229.4 kcal/mol
Frequency: 0.0000
Diversity: 168.08
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
........................(((((((((((..(((....)))..)).......((((.((((..............)))).)))).((((((((((.(((......)))....(((((.((((..((((.(......).)))).)))).)))))...(((.((((((.((.((((..((((((((.......(((((.((.(.((..((((...))))...)).).))..(((((......)))))..))))).((((((((...((.((((..(((..((((..((((.(((((.((.........))..))))).)).))(((((((..(((((....).)))).))))))).....((((.(((...((((...))))....((((((((......(((.....))).....)))))))))))))))....((((((((..............((((..(......)..))))(((...((((................))))...))).)))))))).......)))).)))...))))))...........))))))))............)))........)))))..)))))))))))).)))............))))))).)))..((........)))))))))))...................
Thermodynamic Ensemble Prediction
........................((((((((((((,(({,,|.||||,||{,|,,,.((({.((((,,,.,{,,,,..,.|||}.||}}.(({((({{({.{{,......})),...(((((.((((..((((.{......}.)))).)))).))))).,.|||.{{{|||,||.||||..{{|{{,{{.......((((..((.(.((..((((...))))...)).).))..||||{....,.|}}}|,,|||||,(((((,((...((.((((...|}}}|||,..,,}}}||||(.(({|.....,.||,,|}}}}.,||,|(((((((..(((({....}.)))).)))))))....}||||,||{...|{{|,,,)))).,..((((((((......(((.....))).....))))))))}})}}}},{..((((((((..............((((..{......,..))))(((...((((.,..............))))...))).))))))))..}}...}}}...,}},,)))))).........,.,))),|||,...{,,,|||..,,........})}}}..))}}}))))))).))).....,,,,...})})))).)))...,........||||}}}||}}......}}.}}........

Transcripts

ID Sequence Length GC Content
NM_001286356.2 AGACCAGACCAACAGUAACACCAAGGGCAGGUGGGCAGGCCUCCGCCCU… 724 nt 0.5787
NM_001286357.2 AGACCAGACCAACAGUAACACCAAGGGCAGGUGGGCAGGCCUCCGCCCU… 605 nt 0.5818
NM_001286358.2 AGACCAGACCAACAGUAACACCAAGGGCAGGUGGGCAGGCCUCCGCCCU… 673 nt 0.5825
NM_001286359.2 AGACCAGACCAACAGUAACACCAAGGGCAGGUGGGCAGGCCUCCGCCCU… 727 nt 0.5928
NM_002762.4 AGACCAGACCAACAGUAACACCAAGGGCAGGUGGGCAGGCCUCCGCCCU… 680 nt 0.5838
Summary

Protamines substitute for histones in the chromatin of sperm during the haploid phase of spermatogenesis, and are the major DNA-binding proteins in the nucleus of sperm in many vertebrates. They package the sperm DNA into a highly condensed complex in a volume less than 5% of a somatic cell nucleus. Many mammalian species have only one protamine (protamine 1); however, a few species, including human and mouse, have two. This gene encodes protamine 2, which is cleaved to give rise to a family of protamine 2 peptides. Alternatively spliced transcript variants have also been found for this gene. [provided by RefSeq, Sep 2015]

Forensic Context

No forensic context available.

Genomic Tracks
Track Image