Basic Information
Symbol
RPL27
RNA Class
mRNA
Alias
ribosomal protein L27
L27
eL27
60S ribosomal protein L27
DBA16
large ribosomal subunit protein eL27
Large ribosomal subunit protein eL27
Location (GRCh38)
17:42998273-43002973
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_000988.5
Sequence length
505 nt
GC Content
0.4733
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-156.3 kcal/mol
Thermodynamic ensemble
Free Energy:
-167.16 kcal/mol
Frequency:
0.0000
Diversity:
80.94
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
...(((....)))((((((.......((((.((((((((((((((..((((((....((((((((.......((((....))))...)))))))))))).))..))))).))))......((.(((((((((.((.....)).))))))))).))........)))))))))..((((((((((((((..(((....((.......))..)))..))))))))).))))).......((((.......))))((((((...)))))).((((...((((....)))).))))............(((..(((((.((((((((..(((((((....))))..)))...)))))))).)))))..))).(((((((((((..(((((.....).))))...))...))))).)))).(((.((((((((((((((((..((((((((...)).)))))).)))))...))).)))))))))))............)))))).....
Thermodynamic Ensemble Prediction
...(((,,..,}}{{||{|.,,{({{((({{((((((((((((((..({((((....((((((((.,.....((((....)))).,.)))))))))))).))..))))).))))......,(,(((((((((.{{.....)),))))))))}.,,........)))))))))..{{{{{(((((((((..(((....({.......)}..)))..))))))))).|||||.,.....((((.......)))){(((((...)))))).((((..,(({{....)))}.))))....}}}},...{((..(((((.((((((((..{{{((({....})))..)}}...)))))))).)))))..))).((((((((({(..(((((.....).))))...))...))))}}}))).(((.((((((((((((((((..((((((({...})})))))).)))))...)))}}})))))))))............,})))}.....
Transcripts
| ID | Sequence | Length | GC Content |
|---|---|---|---|
| NM_000988.5 | AGCGGAAGUGUCCUUCUUUCCUUUUUGCUGGUAGGGCCGGGUGGUUGCU… | 505 nt | 0.4733 |
| NM_001349921.2 | AUUCGAAUACUUGAGCUGCCGCGCCCUGCGUUUCCCUCAUGAGCUUCUU… | 595 nt | 0.4908 |
| NM_001349922.2 | AGCGGAAGUGUCCUUCUUUCCUUUUUGCUGGUAGGGCCGGGUGGUUGCU… | 782 nt | 0.5166 |
Summary
Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of four RNA species and approximately 80 structurally distinct proteins. This gene encodes a member of the L27e family of ribosomal proteins and a component of the 60S subunit. A splice site mutation in this gene has been identified in a Diamond-Blackfan anemia (DBA) patient. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Mar 2017]
Forensic Context
No forensic context available.
Genomic Tracks
