Basic Information

Symbol
S100A7
RNA Class
mRNA
Alias
S100 calcium binding protein A7 S100A7c S100 calcium-binding protein A7 (psoriasin 1) S100 calcium binding protein A7 (psoriasin 1) PSOR1 protein S100-A7 psoriasin 1 S100A7C Protein S100-A7 Psoriasin S100 calcium-binding protein A7
Location (GRCh38)
1:153457744-153460651 UCSC Genome Browser
Transcripts
NM_002963.4
BLAST PRIMER
External Database
HGNC NCBI Ensembl UniProt OMIM GTEx

Secondary Structure

MANE Select
NM_002963.4
Sequence length
429 nt
GC Content
0.4895

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-113.6 kcal/mol
Thermodynamic ensemble
Free Energy: -121.27 kcal/mol
Frequency: 0.0000
Diversity: 60.52
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.......((((..............)))).(((....)))(((((.((((((....))))))((((.....))))..(((.(((((((((....(((.(..(((((.((((((((.............)))).)))).).))))..))))..(((((((((.(.((..((((.....))))..)).).))....((((((..........))))))..........((..((((((((.((...(((((((.((((..(((..((((......)))))))..)))).))))))).)).)))))))).))..............))))).))...(((((((....))))))).(((((.............)))))....)))))))))))).......(((((((......))).))))....)))))
Thermodynamic Ensemble Prediction
.......,{{{..............}}}}.(((....})){(({(,((({{{.,,,)}})))((((.....))))..(((.(((((((((....(((.{..(((((.((((((((.............)))).)))).).))))..})))..(((((((,..,.{{..((((,,,..,}}}..},.,,)),},.((((((.,......,.))))))..........((..((((((((.((...(((((((.((((..(((..((({......}))})))..)))).))))))).)).)))))))).))....,.........))))).))..,(((((((....)))))))}(((((.............)))))....)))))))))))).,.....,(({{({......))),}},}....)})),

Transcripts

ID Sequence Length GC Content
NM_002963.4 ACACAUCUCACUCAUCCUUCUACUCGUGACGCUUCCCAGCUCUGGCUUU… 429 nt 0.4895
Summary

The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein differs from the other S100 proteins of known structure in its lack of calcium binding ability in one EF-hand at the N-terminus. The protein is overexpressed in hyperproliferative skin diseases, exhibits antimicrobial activities against bacteria and induces immunomodulatory activities. [provided by RefSeq, Nov 2014]

Forensic Context

No forensic context available.

Genomic Tracks
Track Image