Basic Information
Symbol
SPRR1A
RNA Class
mRNA
Alias
small proline rich protein 1A
cornifin-A
small proline-rich protein 1A
SPRK
19 kDa pancornulin
SPR-IA
small proline-rich protein IA
Cornifin-A
Small proline-rich protein IA
Location (GRCh38)
1:152984081-152985814
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_005987.4
Sequence length
648 nt
GC Content
0.5386
Secondary Structure
Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-174.4 kcal/mol
Thermodynamic ensemble
Free Energy:
-186.21 kcal/mol
Frequency:
0.0000
Diversity:
129.63
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
............(((.......((...(((((((........((((..........))))..((.(((....))))))))))))...))..(((((((.......(((((((..((((..((((((......))).))).....(((......))).....((((...........(((.((.(.(.((((....)))).).).)))))...........))))(((.((...)))))....((((((..(((((((.((((.....(((((..(((...((.((......)).)))))..)))))....(((((.......(((((((((((..((((((((..((((.((((....)).))))))...)))))......)))..))))....)))))))............(((..((((......))))..))))))))..................((......))((.(((....))).))..............)))))))))))..))))))))))...)))))))..(((.....))).((((.............))))))))))).((((((..(((((.(((((.((.((....)).)).))))))))))..))))))...............))).
Thermodynamic Ensemble Prediction
...........{((........((...(((((((........,,{,..........}}}}..((.(((....))))))))))))...))..(((((((.......(((((((..((((..((((((......)))}|||..,..(((......)))..,..|||,...........(((,((,(,{,(({{....|||||..|,||}}}...........)))}{{(.((,.,|,,,}....{(((({.,({(((((.({{(.....(((((..(((...{(.{,......)),,,)))..))))).,..,,||||......(((((((((((..((((((((..((((.((((....)).))))))...)))))......)))..)))}...,))))))),,{.....,,,.{{{..{{((.....,||}}..))}}))})}|}...,}}.........||}}....))}}}|,.....|||.|...........,...))))))))))),,)})))}))))...)))))))..(((.....))).((((.............))))))))))).{((((((.((({{{(((((.((.((....)).)).)))))))))))))))))}.........,,,...,}}.
Summary
A structural constituent of skin epidermis. Involved in keratinocyte differentiation and peptide cross-linking. Located in cornified envelope. [provided by Alliance of Genome Resources, Jul 2025]
Forensic Context
No forensic context available.
Genomic Tracks
