Basic Information

Symbol
SST
RNA Class
mRNA
Alias
somatostatin SMST SST1 somatostatin-14 somatostatin-28 prepro-somatostatin growth hormone release-inhibiting factor Somatostatin Growth hormone release-inhibiting factor
Location (GRCh38)
3:187668912-187670394 UCSC Genome Browser
Transcripts
NM_001048.4
BLAST PRIMER
External Database
HGNC NCBI Ensembl UniProt OMIM GTEx

Secondary Structure

MANE Select
NM_001048.4
Sequence length
607 nt
GC Content
0.5470

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-188.8 kcal/mol
Thermodynamic ensemble
Free Energy: -198.73 kcal/mol
Frequency: 0.0000
Diversity: 158.69
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
.......((((((((.(((((((..(.(((....))).).)))).......))).))))))))((.((((........((((((..(((((((.((.((((....(((((((((((((.(((((.(((((((((..((((.(((((..((....))..))))).))))..))))))).....((((........)))).((((((((((.....((((((((....)))).))))..))))))))))((((((.....))))))....((.(((((((........)))))))))......)).))))).((((...........))))..)).).))))))........((.(((((..((((....))))...))))).))))))..)))).)).)))))..))..)))))).((((((..((((..(((.(((((((..(((..(((((((.....))))).))...)))....(((((....))))).......................................)))))))))).))))..))))))((((...))))....(((....)))...........)))).))...........
Thermodynamic Ensemble Prediction
.......((((({((.((({((({{({{((,,..|||,,.}}}},|,|,}|})}.}}}}}})}{{,{{{{,,...,,,((((((,,((,{{{(,((,((((....{{{{{{{{{{|{|.(((((.({(((((((..((((.(((((..((....))..))))).)))},.))))))).,.,,{|||...,,,.,||}}.((((((((((.....((((((((....)))).))))..))))))))))((((((.....)))))).,,,||.(((((((........)))))))}}......|},||||,,({,(.....,.,}.,)))),.)),).)))))),,....,.{{.(((((.,((((....))))...))))).)}))))..)))).}},))))}..))..)))))).{(((((..{{((,,{{{{({(((({..,,,..,,(((({.....}}))).}}...,}}....(((((....))))).....,.................................})))))))}}.))))..)))))},,||...},},....{{{....,},...........}))).,,...........
Summary

The hormone somatostatin has active 14 aa and 28 aa forms that are produced by alternate cleavage of the single preproprotein encoded by this gene. Somatostatin is expressed throughout the body and inhibits the release of numerous secondary hormones by binding to high-affinity G-protein-coupled somatostatin receptors. This hormone is an important regulator of the endocrine system through its interactions with pituitary growth hormone, thyroid stimulating hormone, and most hormones of the gastrointestinal tract. Somatostatin also affects rates of neurotransmission in the central nervous system and proliferation of both normal and tumorigenic cells. [provided by RefSeq, Jul 2008]

Forensic Context

No forensic context available.

Genomic Tracks
Track Image