Basic Information
Symbol
SYNE2
RNA Class
mRNA
Alias
spectrin repeat containing nuclear envelope protein 2
SYNE-2
DKFZP434H2235
Nesprin-2
NUANCE
NUA
KIAA1011
Nesp2
nuclear envelope spectrin repeat-2
nucleus and actin connecting element
spectrin repeat containing, nuclear envelope 2
EDMD5
KASH2
TROPH
KASH domain-containing protein 2
nesprin 2
nesprin-2 spectrin repeats 3-54
nuclear envelope spectrin repeat protein 2
nucleus and actin connecting element protein
polytrophin
synaptic nuclear envelope protein 2
synaptic nuclei expressed gene 2
Nuclear envelope spectrin repeat protein 2
Nucleus and actin connecting element protein
Protein NUANCE
Synaptic nuclear envelope protein 2
Syne-2
Location (GRCh38)
14:63761899-64226433
UCSC Genome Browser
Transcripts
Secondary Structure
MANE Select
NM_182914.3
Sequence length
21822 nt
GC Content
0.4284
Summary
The protein encoded by this gene is a nuclear outer membrane protein that binds cytoplasmic F-actin. This binding tethers the nucleus to the cytoskeleton and aids in the maintenance of the structural integrity of the nucleus. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009]
Forensic Context
No forensic context available.
Genomic Tracks
