Basic Information

Symbol
TNP1
RNA Class
mRNA
Alias
transition protein 1 spermatid nuclear transition protein 1 transition protein 1 (during histone to protamine replacement) TP1 STP-1 TP-1 Spermatid nuclear transition protein 1
Location (GRCh38)
2:216859458-216860064 UCSC Genome Browser

Secondary Structure

MANE Select
NM_003284.4
Sequence length
407 nt
GC Content
0.4988

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-111.3 kcal/mol
Thermodynamic ensemble
Free Energy: -118.17 kcal/mol
Frequency: 0.0000
Diversity: 88.18
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((......((((((((((.((.((((..(((((.(....................).)))))..((((((((.((....))...))))))))...((((((.......(((((..((...........((....))....((((.....))))......((((....))))....))..))))))))))).(((((((((((.....))))))(((..((((((..........)))))).)))...)))))...((((..(((....((....))....)))..)))).((((....(((.((......)).)))......)))).......)))).)).)))))))))).......(((((((..........))))))).((((.......))))..)).....
Thermodynamic Ensemble Prediction
,(,,,{..((((((((((.((.((((...((({,{,,{,.{{{{{........{,.{|.|||,.((((((((.((....))...))))))))...{{||{|}......{||||,..,...........{{,,.,{{{,..|||,....,|}||...|{{((((.,..,}}}..,,))..}}}}))))))}.|||{{((((((.....))))))(((..((((((..........)))))).)},,,.,,,,}...{(((..(((....((....))....)))..)))}.{{||....(({.{{......)).)))....},)}))..}})..)))).)).)))))))))).......(((((((..,.......))))))).{{{{.....,,))),..,}.....
Summary

Transition protein-1 is a spermatid-specific product of the haploid genome which replaces histone and is itself replaced in the mature sperm by the protamines (see PRM1, MIM 182880; PRM2, MIM 182890) (Luerssen et al., 1990 [PubMed 2249851]).[supplied by OMIM, Mar 2008]

Forensic Context

No forensic context available.

Genomic Tracks
Track Image