Basic Information

Symbol
CCL27
RNA Class
mRNA
Alias
C-C motif chemokine ligand 27 ALP ILC CTACK skinkine ESkine PESKY CTAK CC chemokine ILC IL-11 Ralpha-locus chemokine cutaneous T-cell attracting chemokine small inducible cytokine subfamily A (Cys-Cys), member 27 chemokine (C-C motif) ligand 27 SCYA27 C-C motif chemokine 27 IL-11 R-alpha-locus chemokine small-inducible cytokine A27 Cutaneous T-cell-attracting chemokine Skinkine Small-inducible cytokine A27
Location (GRCh38)
9:34661880-34664048 UCSC Genome Browser

Secondary Structure

MANE Select
NM_006664.4
Sequence length
417 nt
GC Content
0.5348

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-131.8 kcal/mol
Thermodynamic ensemble
Free Energy: -139.11 kcal/mol
Frequency: 0.0000
Diversity: 130.67
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
..(((.(((.(((((.((((...((((((((..((((((.((((((((((.....(((((((((........(((....))).....))))))))).......(((......)))......((((....))))((((((((..(((..((((((........))))))..)))..))..)))))).)))))))))).))..)))).(((.......))).)))))))).))))))))))))...((((...)))).)))...(((((((...((((.((.......(((..(((..(((.(.(((....)))).)))..))).))))).))))..)))))))(((((.(((((...((((....))))(((((.((..............))))))).......))))).)))))..
Thermodynamic Ensemble Prediction
..((,.(,((((,(({((((((,,,,(((((,,.......)))}}.(((((....,||}||,{|...}}}}}...}}}}.)))}.,|{{{(((({{......,{({....,|)|}.}},,)))))}|,,|{{.(((((({,..(((..((((((........))))))..)))..,}..)))))}.,}||||{||{,{{{{({,,.}}}}}}})))).|||},,,}})}}}}}}})))}}}...((((...)))).}}}...(((((((...((((.((....,,.(((..(((..(((.(.(((....)))).)))..))).))))).))))..))))))){{(({.,(({,...((((....))))(((((.((..............))))))).......,}))),))))}..

Transcripts

ID Sequence Length GC Content
NM_006664.4 AAGGAAGAGUCUAGGCUGAGCAACAUGAAGGGGCCCCCAACCUUCUGCA… 417 nt 0.5348
Summary

This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation. [provided by RefSeq, Sep 2014]

Forensic Context

No forensic context available.

Genomic Tracks
Track Image