Forensic RNA Knowledge Base

Basic Information

Symbol

piR-hsa-18724

RNA class

piRNA

Alias

hsa-piR-18497 DQ588409.1 hsa_piRNA_6550 piR-55521 PIR49521 PIR49524 URS0000344135

Location (GRCh38)

15:101760830-101760858

UCSC Genome Browser Search in Marker Scope

Forensic tag(s)

Tissue/body fluid identification

External database

piRBase

piRNAdb

RNAcentral

Sequence & Structure

Transcript

piR-hsa-18724

Sequence length

29 nt

GC content

0.5862

Secondary Structure

Generated by RNAfold

Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.

Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.

Minimum free energy

-5.40 kcal/mol

Thermodynamic ensemble

Free energy: -5.66 kcal/mol

Frequency: 0.6537

Diversity: 0.89

MFE Structure Visualization

Structure Prediction

MFE Structure Prediction

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Thermodynamic Ensemble Prediction

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Forensic Context

A study in humans demonstrated that the expression profiles of 376 piRNAs, identified via massively parallel sequencing from six biological samples, exhibited acceptable discriminating ability for most sample types [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. A study in humans demonstrated that the piR-hsa-18724 is specifically and strongly expressed in semen, showing at least a 4000-fold higher expression compared to venous blood, saliva, menstrual blood, and vaginal secretions, and it was not detectable in saliva [Wang et al. DOI:10.1016/j.fsigen.2019.01.002]. A subsequent review confirmed its specific expression in semen for body fluid identification [Song et al. DOI:10.1007/s00414-023-03091-1].