Basic Information

Symbol
piR-hsa-7193
RNA class
piRNA
Alias
hsa-piR-6960 DQ576872.1 hsa_piRNA_17087 hsa_piR_004987 piR-44984 URS000056EF70 PIR37983
Location (GRCh38)
1:146038042-146038072
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Chronological age estimation
External database
piRBase piRNAdb RNAcentral

Sequence & Structure

Transcript
piR-hsa-7193
Sequence length
31 nt
GC content
0.4839

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-1.40 kcal/mol
Thermodynamic ensemble
Free energy: -2.98 kcal/mol
Frequency: 0.0767
Diversity: 9.34
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the piR-hsa-7193 was not identified among the 376 piRNAs initially characterized from six forensically relevant biological fluids (venous blood, menstrual blood, saliva, semen, vaginal secretions, and skin) using massively parallel sequencing [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. A comprehensive review of non-coding RNA applications in forensic science also did not report the piR-hsa-7193 as a validated marker for body fluid identification, postmortem interval estimation, wound age estimation, age assessment, or cause of death analysis [Li et al. DOI:10.1093/fsr/owad003]. A study in human blood samples identified the piR-hsa-7193 as a piRNA positively correlated with aging, with Pearson correlation coefficients of r = 0.713 in massively parallel sequencing and r = 0.324 in RT-PCR validation [Fang et al. DOI:10.1007/s00414-023-03028-8].