Basic Information

Symbol
piR-hsa-8249
RNA class
piRNA
Alias
hsa-piR-8078 DQ577990.1 hsa_piRNA_15969 hsa_piR_005816 piR-46102 URS0000038E70 PIR39101
Location (GRCh38)
15:62246565-62246624
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
piRBase piRNAdb RNAcentral

Sequence & Structure

Transcript
piR-hsa-8249
Sequence length
31 nt
GC content
0.5484

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-5.80 kcal/mol
Thermodynamic ensemble
Free energy: -6.56 kcal/mol
Frequency: 0.2910
Diversity: 8.49
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((..((.(((....))).))...))))..
Thermodynamic Ensemble Prediction
,{{(,.,,.|||....}||,|,...,))),.
Forensic Context

A study in humans demonstrated that the expression profiles of piwi-interacting RNAs (piRNAs) can discriminate forensically relevant biological fluids, with a panel of 37 piRNA candidates achieving a classification error rate of 0.04 in a PLS-DA model [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. The specific biomarker piR-hsa-8249 was not identified or validated among the 376 initially discovered piRNAs or the subsequently established candidate panels in this investigation. A study in humans using massively parallel sequencing identified the piR-hsa-8249 as an absolute specific marker for semen, demonstrating high specificity in pairwise comparisons with other body fluids/tissues [Liu et al. DOI:10.3390/genes13091530].