Basic Information

Symbol
piR-hsa-26591
RNA class
piRNA
Alias
piR-34441 PIR57486
Location (GRCh38)
6:27297996-27298027
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
piRBase RNAcentral

Sequence & Structure

Transcript
piR-hsa-26591
Sequence length
30 nt
GC content
0.6000

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-7.30 kcal/mol
Thermodynamic ensemble
Free energy: -7.52 kcal/mol
Frequency: 0.7044
Diversity: 1.00
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the piR-hsa-26591 is a potential biomarker for distinguishing saliva from vaginal secretions, as it was validated to be significantly more highly expressed in vaginal secretions (15-fold higher) than in saliva with no overlap in ΔCq value quartiles [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. A review further confirmed its potential for distinguishing these two body fluids in forensic science applications [Li et al. DOI:10.1093/fsr/owad003].