Basic Information

Symbol
piR-hsa-27491
RNA class
piRNA
Alias
hsa-piR-27304 DQ597216.1 hsa_piRNA_26789 hsa_piR_019823 piR-35282 URS000034C6F0 PIR58327
Location (GRCh38)
11:11510564-11510591
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
piRBase piRNAdb RNAcentral

Sequence & Structure

Transcript
piR-hsa-27491
Sequence length
26 nt
GC content
0.4615

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-2.10 kcal/mol
Thermodynamic ensemble
Free energy: -2.48 kcal/mol
Frequency: 0.5433
Diversity: 5.99
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the piR-hsa-27491 was validated as significantly more highly expressed in menstrual blood (163-fold higher) than in venous blood and also showed a statistically significant, higher expression in saliva compared to vaginal secretions [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. The literature review further notes its potential for distinguishing venous blood from menstrual blood and for distinguishing saliva from vaginal secretions [Li et al. DOI:10.1093/fsr/owad003]. A study in humans using massively parallel sequencing identified the piR-hsa-27491 as an absolute specific marker for semen, demonstrating high specificity in four out of five pairwise comparisons and high expression levels [Liu et al. DOI:10.3390/genes13091530].