Basic Information

Symbol
piR-hsa-28223
RNA class
piRNA
Alias
hsa-piR-28096 DQ598008.1 hsa_piRNA_25997 hsa_piR_020388 piR-36074 URS0000147B41 PIR59119
Location (GRCh38)
11:76235867-76235896
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification
External database
piRBase piRNAdb RNAcentral

Sequence & Structure

Transcript
piR-hsa-28223
Sequence length
30 nt
GC content
0.5667

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-3.80 kcal/mol
Thermodynamic ensemble
Free energy: -4.59 kcal/mol
Frequency: 0.2766
Diversity: 8.60
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
((((....))))..((((......))))..
Thermodynamic Ensemble Prediction
{(((,...}}}}..,|||,.....}}})..
Forensic Context

A study in humans demonstrated that the expression profile of the piR-hsa-28223 provided valuable information for discriminating forensically relevant biological fluids, with a panel of 37 candidate piRNAs achieving a classification error rate of 0.04 in a PLS-DA model [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. A study in human forensic samples identified the piR-hsa-28223 as an absolute specific marker (ASM) for vaginal secretion, demonstrating high specificity with level III specificity in one pairwise comparison and level II in four comparisons, alongside moderate expression [Liu et al. DOI:10.3390/genes13091530].