Basic Information

Symbol
piR-hsa-28478
RNA class
piRNA
Alias
hsa-piR-28351 DQ598263.1 hsa_piRNA_25742 hsa_piR_020548 piR-36329 URS0000395FF1 PIR59374
Location (GRCh38)
2:229180869-229180897
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Chronological age estimation Tissue/body fluid identification Postmortem interval inference Cause of death analysis
External database
piRBase piRNAdb RNAcentral

Sequence & Structure

Transcript
piR-hsa-28478
Sequence length
29 nt
GC content
0.6552

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-7.20 kcal/mol
Thermodynamic ensemble
Free energy: -7.70 kcal/mol
Frequency: 0.4431
Diversity: 5.42
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the piR-hsa-28478 was not identified among the 376 piRNAs initially characterized from forensically relevant biological fluids, and subsequent validation of selected candidates did not include this specific piRNA [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. A review of non-coding RNAs in forensic science also did not report any specific findings or applications for the piR-hsa-28478 in areas such as body fluid identification, postmortem interval estimation, or cause of death determination [Li et al. DOI:10.1093/fsr/owad003]. A study in humans demonstrated that piR-hsa-28478, identified via massively parallel sequencing in aged blood samples, is negatively correlated with aging (Pearson r = -0.584 in MPS, r = -0.499 in RT-PCR) [Fang et al. DOI:10.1007/s00414-023-03028-8].