Basic Information

Symbol
piR-hsa-28846
RNA class
piRNA
Alias
hsa-piR-28734 DQ598646.1 hsa_piRNA_25359 hsa_piR_020813 piR-36712 URS0000025E11 PIR59757
Location (GRCh38)
1:30968166-30968195
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Sudden cardiac death diagnosis
External database
piRBase piRNAdb RNAcentral

Sequence & Structure

Transcript
piR-hsa-28846
Sequence length
30 nt
GC content
0.4667

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-4.60 kcal/mol
Thermodynamic ensemble
Free energy: -5.27 kcal/mol
Frequency: 0.3381
Diversity: 7.98
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that piR-hsa-28846 was significantly upregulated in the serum of patients with acute myocardial infarction (AMI) compared to healthy controls, showing high diagnostic value with an AUC of 0.838 [Huang et al. DOI:10.1016/j.jjcc.2023.06.015]. A study in humans using massively parallel sequencing of small RNAs in six forensic body fluids/tissues identified the piR-hsa-28846 as an absolute specific marker (ASM) for venous blood, where it was discovered in this research and demonstrated high specificity [Liu et al. DOI:10.3390/genes13091530].