Basic Information

Symbol
piR-hsa-27622
RNA class
piRNA
Alias
hsa-piR-27435 DQ597347.1 hsa_piRNA_26658 hsa_piR_019914 piR-35413 URS000001A289 PIR58458
Location (GRCh38)
Forensic tag(s)
Tissue/body fluid identification

Sequence & Structure

Transcript
piR-hsa-27622
Sequence length
32 nt
GC content
0.6250

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-7.90 kcal/mol
Thermodynamic ensemble
Free energy: -8.21 kcal/mol
Frequency: 0.6005
Diversity: 1.83
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the piR-hsa-27622 is a potential biomarker for distinguishing venous blood from menstrual blood, as it was validated to be significantly more highly expressed in menstrual blood (66-fold higher) with no overlap in individual ΔCq values between the two biofluids [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. A review further highlighted its potential for this specific forensic body fluid identification application [Li et al. DOI:10.1093/fsr/owad003].