Basic Information

Symbol
piR-hsa-28646
RNA class
piRNA
Alias
hsa-piR-28533 DQ598445.1 hsa_piRNA_25560 hsa_piR_020668 piR-36511 URS00000C0E02 PIR59556
Location (GRCh38)
Forensic tag(s)
Sudden cardiac death diagnosis

Sequence & Structure

Transcript
piR-hsa-28646
Sequence length
28 nt
GC content
0.5714

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-13.30 kcal/mol
Thermodynamic ensemble
Free energy: -13.38 kcal/mol
Frequency: 0.8812
Diversity: 0.24
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the piR-hsa-28646 was significantly upregulated in the serum of patients with acute myocardial infarction (AMI) compared to healthy controls, showing high diagnostic value with an area under the curve of 0.838 [Huang et al. DOI:10.1016/j.jjcc.2023.06.015].