Basic Information

Symbol
piR-hsa-993
RNA class
piRNA
Alias
hsa-piR-816 DQ570728.1 hsa_piRNA_31231 hsa_piR_000586 piR-30840 URS00003C0FA7 PIR31839
Location (GRCh38)
5:138561046-138561073
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Tissue/body fluid identification Chronological age estimation
External database
piRBase piRNAdb RNAcentral

Sequence & Structure

Transcript
piR-hsa-993
Sequence length
28 nt
GC content
0.4286

Secondary Structure

Generated by RNAfold
Minimum free energy (MFE) structure:
Secondary structure that contributes a minimum of free energy.
Ensemble properties:
Thermodynamic properties of the Boltzmann ensemble.
Minimum free energy
-0.60 kcal/mol
Thermodynamic ensemble
Free energy: -1.23 kcal/mol
Frequency: 0.3612
Diversity: 4.17
MFE Structure Visualization
Structure Prediction
MFE Structure Prediction
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Thermodynamic Ensemble Prediction
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Forensic Context

A study in humans demonstrated that the expression profile of the piR-hsa-993 provided valuable information for discriminating forensically relevant biological fluids [Wang et al. DOI:10.1016/j.fsigen.2019.07.015]. A study in humans using massively parallel sequencing of small RNAs in six forensic body fluids/tissues identified the piR-hsa-993 as an absolute specific marker for venous blood, where it was discovered in this research and demonstrated high specificity and very high expression [Liu et al. DOI:10.3390/genes13091530]. Another study in humans developed a forensic age estimation model for aged blood samples using massively parallel sequencing and real-time PCR, where the piR-hsa-993 was identified as an age-related piRNA positively correlated with aging in sequencing data [Fang et al. DOI:10.1007/s00414-023-03028-8].