Basic Information

Symbol
CHAER1
RNA class
lncRNA
Alias
Cardiac Hypertrophy Associated Epigenetic Regulator 1 Chaer HSALNG0034607
Location (GRCh38)
4:56688410-56706653
UCSC Genome Browser Search in Marker Scope
Forensic tag(s)
Sudden cardiac death diagnosis
External database
HGNC NCBI Ensembl RNAcentral

Transcripts

ID Sequence Length GC content
HSALNT0072602 UUUUUGCUGCUGAUCUCUACAGGAAAGCAAAAAGCCCCGAAGAGCCUGG… 1255 nt 0.4494
HSALNT0072603 CCGAGAUUGAGCCACUGCACUCCAGCCUGGGCAACAGAGCAACACUCUG… 4506 nt 0.4432
HSALNT0072604 CCGAGAUUGAGCCACUGCACUCCAGCCUGGGCAACAGAGCAACACUCUG… 4949 nt 0.4459
HSALNT0072605 CCGAGAUUGAGCCACUGCACUCCAGCCUGGGCAACAGAGCAACACUCUG… 5000 nt 0.4454
HSALNT0072606 CCGAGAUUGAGCCACUGCACUCCAGCCUGGGCAACAGAGCAACACUCUG… 7326 nt 0.4429
HSALNT0072607 CCGAGAUUGAGCCACUGCACUCCAGCCUGGGCAACAGAGCAACACUCUG… 9180 nt 0.4428
HSALNT0319768 GUUAGCACAGUAGCUGGGCCCCUGAACCCUCUACAGGCCUCCCAAGCUG… 2430 nt 0.4379
HSALNT0319769 UGUUGUUAUUGUUGUUUAAAUCUUCCUGGAAGGCAGAAAGAAAGAGAUA… 1845 nt 0.4396
HSALNT0319770 UGUUGUUAUUGUUGUUUAAAUCUUCCUGGAAGGCAGAAAGAAAGAGAUA… 2056 nt 0.4377
HSALNT0319771 UGUUGUUAUUGUUGUUUAAAUCUUCCUGGAAGGCAGAAAGAAAGAGAUA… 1596 nt 0.4536
Summary

Predicted to be involved in several processes, including cardiac muscle hypertrophy in response to stress; epigenetic regulation of gene expression; and protein-RNA complex assembly. Predicted to be part of ESC/E(Z) complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Jul 2025]

Forensic Context

A review of long noncoding RNAs in cardiovascular diseases noted that the CHAER1 increases pro-hypertrophic gene expression by interacting with PRC2 to disinhibit hypertrophic gene expression in cardiac hypertrophy [Chih-Fan Yeh et al. DOI:10.1186/s12929-020-00647-w].